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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
19.7
Human Site:
T469
Identified Species:
36.11
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
T469
P
A
S
S
K
H
K
T
A
E
R
Q
E
K
G
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
T472
Q
I
L
P
K
H
K
T
N
E
K
Q
E
K
S
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
T469
P
A
S
S
K
H
K
T
T
E
R
Q
E
K
G
Dog
Lupus familis
XP_534693
2280
250152
T539
P
A
S
K
H
K
T
T
E
R
P
E
K
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
T464
P
A
S
S
K
H
K
T
T
E
R
Q
E
K
G
Rat
Rattus norvegicus
NP_001101807
1374
149708
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
T454
P
V
A
A
K
H
K
T
N
E
K
Q
E
K
G
Chicken
Gallus gallus
XP_415317
2195
241321
A449
P
A
S
S
K
H
K
A
T
E
R
Q
D
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
S416
S
V
W
D
F
V
E
S
S
Q
R
S
Q
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
P611
T
P
A
P
S
P
H
P
N
S
A
H
S
Q
P
Honey Bee
Apis mellifera
XP_393643
1982
216109
S319
T
P
L
S
P
P
S
S
P
A
S
C
E
H
P
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
L781
R
E
Y
H
L
K
D
L
P
K
K
I
Q
K
Y
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
53.3
93.3
26.6
N.A.
93.3
0
N.A.
66.6
80
N.A.
6.6
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
60
93.3
40
N.A.
93.3
0
N.A.
86.6
86.6
N.A.
40
N.A.
13.3
20
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
16
8
0
0
0
8
8
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
8
% D
% Glu:
0
8
0
0
0
0
8
0
8
47
0
8
47
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
39
% G
% His:
0
0
0
8
8
47
8
0
0
0
0
8
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
47
16
47
0
0
8
24
0
8
54
0
% K
% Leu:
0
0
16
0
8
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% N
% Pro:
47
16
0
16
8
16
0
8
16
0
8
0
0
0
16
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
47
16
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
39
0
0
0
0
% R
% Ser:
8
0
39
39
8
0
8
16
8
8
8
8
8
0
16
% S
% Thr:
16
0
0
0
0
0
8
47
24
0
0
0
0
0
0
% T
% Val:
0
16
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _